1579302-93-4Relevant academic research and scientific papers
Copper-catalyzed iminohalogenation of γ, δ-unsaturated oxime esters with halide salts: Synthesis of 2-halomethyl pyrrolines
Chen, Chen,Ding, Jie,Wang, Yuebo,Shi, Xiaonan,Jiao, Dequan,Zhu, Bolin
, (2019)
A copper-catalyzed iminohalogenation of unactivated alkenes of γ, δ-unsaturated oxime esters is achieved by using readily available halide salts. Utilizing this protocol, a sequence of structurally diversiform 2-halomethyl pyrrolines are efficiently synthesized and a mechanism involving iminyl radical intermediates, which were initiated by Cu(I) species, was proposed.
A simple route to functionalized Δ1-pyrrolines
Bingham, Matilda,Moutrille, Cecile,Zard, Samir Z.
, p. 953 - 960 (2014/01/17)
Treatment of -unsaturated oxime esters with cupric acetate or ferric chloride in acetic acid / t-butanol or in t-butanol alone leads to the formation of vinyl- or chloroalkyl- substituted !1-pyrrolines in moderate to good yield.
