157985-07-4

Basic information

• Product Name: (-)-(3R,5S)-5-methyl-3-phenylmorpholin-2-one
• Synonyms: (-)-(3R,5S)-5-methyl-3-phenylmorpholin-2-one
• CAS NO: 157985-07-4
• Molecular Weight: 191.23
• Mol File: 157985-07-4.mol

Chemical Properties

• CAS DataBase Reference: (-)-(3R,5S)-5-methyl-3-phenylmorpholin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(3R,5S)-5-methyl-3-phenylmorpholin-2-one(157985-07-4)
• EPA Substance Registry System: (-)-(3R,5S)-5-methyl-3-phenylmorpholin-2-one(157985-07-4)

Safety Data

• Hazardous Substances Data: 157985-07-4(Hazardous Substances Data)

Upstream product

• 261963-23-9 (-)-(R)-(phenyl)(phenylmethoxycarbonylamino)acetic acid 2-oxo-propyl ester 
• 157985-01-8 5-methyl-3R-phenyl-3,6-dihydro-[1,4]oxazin-2-one 

Downstream Products

• 2749-11-3 (S)-Alaninol 

Relevant articles and documents

A general synthesis of enantiopure 1,2-aminoalcohols via chiral morpholinones

Eleven optically active 1,2-aminoalcohols 20a-i and 26b-c were prepared from D-phenylglycine via cyclic imines 7b-i (or enamine 7a). The key step of the strategy is the diastereoselective reduction of chiral oxazinones 7a-i.

ASYMMETRIC SYNTHESIS WITH CHIRAL HYDROGENOLYSABLE AMINES: A NEW ROUTE TO ENANTIOPURE ETHANOLAMINES

Enantiopure ethanolamines have been obtained via diastereoselective reduction of chiral 2,3-dihydro-6H-1,4-oxazin-2-ones.