157996-62-8

Basic information

• Product Name: 2,7-dinitroacridin-9-amine
• Synonyms: 2,7-Dinitroacridin-9-amine; 9-acridinamine, 2,7-dinitro-
• CAS NO: 157996-62-8
• Molecular Formula: C₁₃H₈N₄O₄
• Molecular Weight: 284.227
• Mol File: 157996-62-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 583.9°C at 760 mmHg
• Flash Point: 306.9°C
• Density: 1.607g/cm³
• Vapor Pressure: 1.28E-13mmHg at 25°C
• Refractive Index: 1.825
• CAS DataBase Reference: 2,7-dinitroacridin-9-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,7-dinitroacridin-9-amine(157996-62-8)
• EPA Substance Registry System: 2,7-dinitroacridin-9-amine(157996-62-8)

Safety Data

• Hazardous Substances Data: 157996-62-8(Hazardous Substances Data)

Upstream product

• 110166-26-2 10H-Acridin-9-ylideneamine 
• 134-50-9 acridin-9-amine hydrochloride 
• 57310-36-8 2,7-dinitro-10H-acridin-9-one 
• 110166-26-2 aminacrine 

Relevant articles and documents

Enhancement of mutagenic activity of 9-aminoacridine by introducing a nitro group into the molecule.

Mutagenic activity and DNA intercalation were examined for 9-aminoacridine (9-AA) and its derivatives. Introduction of a nitro group into the 9-AA molecule was found to enhance the activity enormously as was detected by the Ames test. Acetylation of amino group at 9-position of acridine ring inhibited the intercalation, the frameshift activity disappearing. Rat liver S9 converted 9-AA metabolically to 9-amino-2-hydroxyacridine.