1579996-35-2

Upstream product

• 155931-85-4 (2R,3R,4S)-3,4-bis(benzyloxy)-5-oxo-1-(trityloxy)pentan-2-yl formate 
• 1579996-32-9 (2R,3R,4R)-2,3-bis(benzyloxy)-5-(trityloxy)pentane-1,4-diol 
• 129870-14-0 3,4-di-O-benzyl-6-O-trityl-D-glucal 
• 1579996-33-0 (2R,3S,4R)-2,3-bis(benzyloxy)-5-(trityloxy)pentane-1,4-diyl dimethanesulfonate 
• 1579996-34-1 (2S,3R,4R)-1-benzyl-3,4-bis(benzyloxy)-2-(trityloxymethyl)-pyrrolidine 

Downstream Products

• 1579996-45-4 tert-butyl (2S,3R,4R)-3,4-bis(benzyloxy)-2-(hydroxymethyl)pyrrolidine-1-carboxylate 
• 105990-42-9 (2S,3R,4R)-2-(hydroxymethyl)pyrrolidine-3,4-diol 
• 1579996-43-2 C₁₉H₂₃NO₃ 
• 1579996-47-6 C₂₄H₂₉NO₅ 

Relevant academic research and scientific papers

Synthesis of pyrrolidine iminosugars, (-)-lentiginosine, (-)-swainsonine and their 8a-epimers from d-glycals

Synthesis of pyrrolidine iminosugars has been described from d-glycals via dihydroxylation, oxidative cleavage and double nucleophilic displacement as the key steps. The pyrrolidines obtained have been utilized for the synthesis of important bicyclic iminosugars, viz. (-)-lentiginosine and (-)-swainsonine and their 8a-epimers, which are known to be glycosidase inhibitors.