1579999-02-2

Upstream product

• 42122-73-6 diethyl 5-aminoisophthalate 
• 106-50-3 1,4-phenylenediamine 
• 99-31-0 5-aminoisophthalic acid 
• 1579998-97-2 (E)-diethyl 5-((3-(1,3-dioxoisoindolin-2-yl)phenyl)diazenyl)isophthalate 
• 365549-28-6 diethyl 5-nitroso-isophthalate 

Downstream Products

• 1579999-09-9 (E)-diethyl 5-((3-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)phenyl)diazenyl)isophthalate 
• 1579999-14-6 (Z)-diethyl 5-((3-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)phenyl)diazenyl)isophthalate 

Relevant academic research and scientific papers

Azo aryl urea derivative, and preparation method and application thereof

The invention relates to an azo aryl urea derivative, and a preparation and an application thereof, and concretely discloses a compound represented by formula (I), or an optical isomer, a cis-trans-isomer or a pharmaceutically acceptable salt thereof, and a preparation method thereof. Definitions of substituent groups in the general formula are described in the specification and claims. The invention further discloses a composition containing the above compound, and an application thereof. The compound has excellent anticancer activity on HepG2 liver cancer cells, MGC803 gastric cancer cells,HCT116 colon cancer and the like.

Photoswitchable thioureas for the external manipulation of catalytic activity

A series of azobenzene-based thiourea catalysts have been developed with the aim of achieving control over the catalytic activity by the use of light. The conceptual design of these systems relies on the inactivation by means of intramolecular hydrogen bonding, only likely to take place in one of their isomeric forms. After fine structure modulation of the catalyst a substantial difference in activity has been observed between the irradiated and the nonirradiated reaction. Furthermore, the system allowed in situ manipulation of the catalyst activity during the course of a given experiment.