15803-27-7

Basic information

• Product Name: ethyl 4,5-diMethyl-1H-pyrazole-3-carboxylate
• Synonyms: ethyl 4,5-diMethyl-1H-pyrazole-3-carboxylate;1-(1,2-diphenylethoxy)propan-2-ol;1H-Pyrazole-3-carboxylic acid, 4,5-dimethyl-, ethyl ester
• CAS NO: 15803-27-7
• Molecular Formula: C8H12N2O2
• Molecular Weight: 168.19308
• Mol File: 15803-27-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 309.8±37.0 °C(Predicted)
• Appearance: /
• Density: 1.136±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 12.55±0.50(Predicted)
• CAS DataBase Reference: ethyl 4,5-diMethyl-1H-pyrazole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4,5-diMethyl-1H-pyrazole-3-carboxylate(15803-27-7)
• EPA Substance Registry System: ethyl 4,5-diMethyl-1H-pyrazole-3-carboxylate(15803-27-7)

Safety Data

• Hazardous Substances Data: 15803-27-7(Hazardous Substances Data)

Usage

General Description

Ethyl 4,5-diMethyl-1H-pyrazole-3-carboxylate is a chemical compound with a molecular formula C8H12N2O2. It is a pyrazole derivative with two methyl groups and an ethyl ester at the 3-position of the pyrazole ring. ethyl 4,5-diMethyl-1H-pyrazole-3-carboxylate has applications in pharmaceutical and agrochemical research, as it can serve as a building block for the synthesis of biologically active compounds. It may also have potential uses in the development of new drugs and crop protection agents. Additionally, it is important to handle this chemical with care and use proper safety precautions, as it may have hazardous properties.

Upstream product

• 95-92-1 oxalic acid diethyl ester 
• 78-93-3 butanone 
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• 623-73-4 diazoacetic acid ethyl ester 

Downstream Products

• 115294-67-2 1,3,4-trimethyl-1H-pyrazole-5-carboxylic acid 

Relevant articles and documents

Preparation method of 3, 4-dimethylpyrazole-5-formate compound

The invention provides a preparation method of a 3, 4-dimethylpyrazole-5-formate compound. According to the method, 2-butanone and oxalic acid diester serve as raw materials, a 3-methyl acetylacetonate compound is prepared in a high-yield and high-regioselectivity mode under the catalysis of an organic annular secondary amine catalyst, the 3-methyl acetylacetonate compound reacts with hydrazine, and the 3, 4-dimethylpyrazole-5-formate compound is prepared in a high-yield mode. According to the preparation method, organic nitrogen-containing cyclic secondary amine compounds such as pyrroline, piperidine and morpholine are used as catalysts, and alcohols such as methanol and ethanol are used as solvents for reaction. The method has the characteristics of relatively mild reaction conditions, simplicity and convenience in operation, high regioselectivity, high yield and the like, and the synthesized 3, 4-dimethylpyrazole-5-formate compound can be used for preparing cyenopyrafen acaricides.

PROCESS FOR THE SYNTHESIS OF SUBSTITUTED PYRAZOLES

A process for the preparation of 4,5-di- and 2,4,5-trisubstituted pyrazole 3-carboxylates from 3-acyloxirane-2-carboxylates and hydrazine compounds.