1580490-74-9Relevant academic research and scientific papers
Efficient bromination of olefins, alkynes, and ketones with dimethyl sulfoxide and hydrobromic acid
Song, Song,Li, Xinwei,Sun, Xiang,Yuan, Yizhi,Jiao, Ning
, p. 3285 - 3289 (2015)
The oxidative bromination of olefins, alkynes, and ketones has been developed with HBr as the brominating reagent and DMSO as the mild oxidant. The simple conditions, high bromide-atom-economy, as well as easy accessibility and low cost of DMSO and HBr make the present strategy prospective for the synthesis of dibrominated alkanes, dibrominated alkenes and α-bromoketones.
Halocarbocyclization versus dihalogenation: Substituent directed iodine(iii) catalyzed halogenations
Stodulski, Maciej,Goetzinger, Alissa,Kohlhepp, Stefanie V.,Gulder, Tanja
supporting information, p. 3435 - 3438 (2014/03/21)
The nucleophilicity of the substituents in iodobenzene pre-catalysts have a huge impact on product selectivity in iodine(iii) triggered halogenations, steering the reactivity from solely carbocyclizations towards dihalogenations. Utilizing this catalyst-dependent reactivity a diastereo- and chemoselective dihalogenation method was established allowing the conversion of structurally and electronically diverse unsaturated compounds in excellent yields.
