158062-58-9Relevant academic research and scientific papers
N-(2-benzoylphenyl)-L-tyrosine PPARγ agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents
Henke, Brad R.,Blanchard, Steven G.,Brackeen, Marcus F.,Brown, Kathleen K.,Cobb, Jeff E.,Collins, Jon L.,Harrington Jr., W. Wallace,Hashim, Mir A.,Hull-Ryde, Emily A.,Kaldor, Istvan,Kliewer, Steven A.,Lake, Debra H.,Leesnitzer, Lisa M.,Lehmann, Jürgen M.,Lenhard, James M.,Orband-Miller, Lisa A.,Miller, John F.,Mook Jr., Robert A.,Noble, Stewart A.,Oliver Jr., William,Parks, Derek J.,Plunket, Kelli D.,Szewczyk, Jerzy R.,Willson, Timothy M.
, p. 5020 - 5036 (2007/10/03)
We have identified a novel series of antidiabetic N-(2-benzoylphenyl)- L-tyrosine derivatives which are potent, selective PPARγ agonists. Through the use of in vitro PPARγ binding and functional assays (2S)-3-(4- (benzyloxy)phenyl)-2-((1-methyl-3-oxo-3-ph
Heterocyclic compounds as pharmaceutical
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, (2008/06/13)
Compounds of Formula (I) or a tautomeric form thereof and/or a pharmaceutically acceptable salt thereof, and/or a pharmaceutically acceptable solvate thereof, wherein A1, A2, A3, R2, X, Y and n are as define
