158070-22-5Relevant academic research and scientific papers
The intramolecular silyl-modified sakurai (ISMS) reaction. Synthetic studies towards ambruticine
Marko, Istvan E.,Bayston, Daniel J.
, p. 7141 - 7156 (1994)
The ISMS reaction has been used to efficiently construct the right-hand portion 3 of the antifungal antibiotic ambruticine 1.
Towards the total synthesis of ambruticin: Preparation of the fully functionalised righ-hand portion using the Intramolecular Silyl-Modified Sakurai (ISMS) annulation
Marko,Bayston
, p. 297 - 304 (2007/10/03)
The concise synthesis of the fully functionalised right-hand dihydropyran subunit of the antifungal antibiotic ambruticin (1), using the ISMS annulation as the key-step, is described.
