158075-64-0Relevant academic research and scientific papers
Method for preparing a benzaldehyde intermediate
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, (2008/06/13)
A method is provided for preparing a chiral benzaldehyde of the structure STR1 by acylating an anhydride of the structure STR2 with a chiral oxazolidine of the structure STR3 where Q is MgHal or Li, and X, Y and Z are as described herein, to form a keto acid which is reduced and cyclized. The resulting benzaldehyde may be used in making the final anti-thrombotic - anti-vasospastic compounds. Novel intermediates are also provided.
