158081-98-2

Usage

Uses

Used in Pharmaceutical Applications:
Anolignan B is used as an anti-HIV agent for its ability to inhibit the HIV-1 reverse transcriptase enzyme, which plays a crucial role in the replication of the virus. This inhibition can potentially slow down the progression of the disease in infected individuals.
Used in Antiviral Research:
Anolignan B serves as a valuable compound in the development of new antiviral drugs. Its unique structure and ability to inhibit the HIV-1 reverse transcriptase enzyme make it a promising candidate for further research and potential application in the treatment of other viral infections.
Used in Drug Delivery Systems:
Similar to gallotannin, anolignan B could potentially be incorporated into novel drug delivery systems to enhance its bioavailability, delivery, and therapeutic outcomes. This could involve the use of organic or metallic nanoparticles as carriers for more efficient administration and targeting of the compound to affected cells or tissues.

InChI:InChI=1/C18H18O2/c1-13(11-15-3-7-17(19)8-4-15)14(2)12-16-5-9-18(20)10-6-16/h3-10,19-20H,1-2,11-12H2

Upstream product

• 397872-64-9 2,3-bis[(4-benxenesulfonyloxyphenyl)methyl]-1,3-butadiene 
• 123-08-0 4-hydroxy-benzaldehyde 
• 101911-57-3 1-(benzyloxy)-4-(prop-2-yn-1-yl)benzene 
• 836-42-0 4-benzyloxybenzyl chloride 
• 936342-53-9 (3-(4-(benzyloxy)phenyl)prop-1-ynyl)trimethylsilane 
• 397872-63-8 acetic acid 3-[acetoxy-(4-benzenesulfonloxyphenyl)-methyl]-1-(4-benzenesulfonyloxyphenyl)-2-methylenebut-3-enyl ester 
• 397872-62-7 acetic acid 4-acetoxy-1,4-bis-(4-benzenesulfonyloxyphenyl)but-2-ynyl ester 
• 397872-81-0 C₆H₄CHOOSO₂C₆H₅C₂H₂COHC₆H₄OSO₂C₆H₅ 
• 397872-61-6 benzenesulfonic acid 4-(1-hydroxyprop-2-ynyl)phenyl ester 
• 13493-50-0 4-hydroxybenzaldehyde benzenesulfonate ester 

Relevant academic research and scientific papers

Palladium-Catalyzed Tail-to-Tail Reductive Dimerization of Terminal Alkynes to 2,3-Dibranched Butadienes

The palladium-catalyzed tail-to-tail reductive dimerization of terminal alkynes is described for the first time. Aromatic terminal alkynes bearing diverse and sensitive functional groups as well as aliphatic terminal alkynes are efficiently transformed to 2,3-dibranched butadienes. The key to achieve a selective tail-to-tail reductive dimerization reaction is to control appropriately the acidity of the reaction solution, which is accomplished by a combined use of pivalic acid and para-toluenesulfonic acid. The tail-to-tail reductive dimerization reaction is proposed to proceed via a cationic alkenyl palladium intermediate under acidic conditions.

Syntheses of anolignans A and B using ruthenium-catalyzed cross-enyne metathesis

Anolignans A and B were synthesized using ruthenium-catalyzed cross-enyne metathesis as the key steps. The 1,3-diene moieties of these natural products were constructed by the introduction of the methylene parts of ethylene into alkyne using Grubbs' catalyst.