158151-20-3Relevant academic research and scientific papers
A concise synthesis of two pyrroles of marine origin
Jefford, Charles W.,Sienkiewicz, Krzysztof,Thornton, Steven R.
, p. 6271 - 6274 (1994)
2-Ethanolamine and (2R)-2-aminopropanol were converted into their N-pyrrole derivatives, 14 and 15, by reaction with 2,5-dimethoxytetrahydrofuran. The acetoxyacetyl derivatives of 14 and 15 were prepared and submitted to BBr3-promoted rearrangement. Acetylation of the resulting (2-acetoxyacetyl)pyrrol-1-yl-2-ethanol and 2-propanol furnished the corresponding acetates.
The synthesis of chiral 1-(1H-pyrrole) derivatives
Jefford, Charles W.,De Villedon De Naide, Fabienne,Sienkiewicz, Krzysztof
, p. 1069 - 1076 (2007/10/03)
Enantiomerically pure primary amines possessing an epimerizable center, such as α-amino acids and their ester hydrochlorides, undergo condensation with tetrahydro-2,5-dimethoxyfuran 2 in acetic acid or acetic acid containing sodium acetate at 80°C for 30
