1581705-52-3Relevant academic research and scientific papers
Copper-catalyzed oxidative coupling of formamides with salicylaldehydes: Synthesis of carbamates in the presence of a sensitive aldehyde group
Barve, Balaji D.,Wu, Yang-Chang,El-Shazly, Mohamed,Chuang, Da-Wei,Cheng, Yuan-Bin,Wang, Jeh-Jeng,Chang, Fang-Rong
, p. 3206 - 3214 (2014/05/06)
A diverse library of novel carbamates was synthesized utilizing copper-catalyzed oxidative C-O coupling of formamides and salicylaldehydes. Sensitive aldehyde groups remained intact in the presence of an oxidant and a transition-metal salt. Salicylaldehydes bearing electron-donating, electron-withdrawing, and halogen groups as well as 1-hydroxy-2-naphthaldehydes provided the desired carbamates in good to excellent yields.
