1581719-29-0Relevant articles and documents
Facilitating Ir-Catalyzed C-H Alkynylation with Electrochemistry: Anodic Oxidation-Induced Reductive Elimination
Shan, Chuan,Shi, Xiaodong,Wang, Chenhuan,Wei, Jingwen,Wojtas, Lukasz,Xie, Yan,Ye, Xiaohan,Zhang, Shuyao
, p. 11693 - 11699 (2020/11/27)
An electrochemical approach in promoting directed C-H alkynylation with terminal alkyne via iridium catalysis is reported. This work employed anodic oxidation of Ir(III) intermediate (characterized by X-ray crystallography) to promote reductive elimination, giving the desired coupling products in good yields (up to 95%) without the addition of any other external oxidants. This transformation is suitable for various directing groups with H2 as the only byproduct, which warrants a high atom economy and practical oxidative C-C bond formation under mild conditions.