158199-52-1Relevant academic research and scientific papers
Stereoselective intramolecular acylation of y'-benzoyloxyphosphine oxides with an internal chlorotrimethylsilane trap: Isolation of silylated tetrahedral intermediates
Feeder, Neu,Hutton, Gordon,Nelson, Adam,Warren, Stuart
, p. 3413 - 3424 (2007/10/03)
The kinetic products of the intramolecular acylation of y'-benzoyloxyphosphine oxides were revealed by conducting the reaction in the presence of an internal trapping agent. A high level of stereocontrol over the formation of both ' : ' the stereogenic centre a to phosphorus and the hemiacetal centre was observed. The stereochemistry of the products was determined by X-ray crystallography and 'H NMR and the stereoselectivity of the reaction is explained in terms of the known structure and configurational instability of lithiated phosphine oxides. The Royal Society of Chemistry 1999.
Stereoselective Acyl Transfer Reactions controlled by the Diphenylphosphinoyl Group: X-ray Structures of Stable Crystalline Silylated Tetrahedral Intermediates
Feeder, Neil,Hutton, Gordon,Warren, Stuart
, p. 5911 - 5914 (2007/10/02)
Acyl transfer with LDA on benzoates of single diastereoisomers of 3-hydroxyalkyldiphenylphosphine oxides in the presence of trimethylsilyl chloride gives silylated tetrahedral intermediates in carbonyl displacement reactions with the stereochemically cont
