158227-05-5Relevant academic research and scientific papers
Oligodeoxyribonucleotides covalently linked via nucleic bases with 3'-5' and 5'-5' polarities
Asseline,Thuong
, p. 889 - 893 (1995)
The solid-phase preparation of oligodeoxyribonucleotides covalently linked via nucleic bases with normal (3'-5') or inverted (5'-5') polarities is reported. The key-step of these syntheses is the preparation of the tethered dimers.
5'-5' tethered oligonucleotides via nucleic bases: A potential new set of compounds for alternate strand triple-helix formation
Asseline,Thuong
, p. 5221 - 5224 (2007/10/02)
The solid-phase synthesis of 5'-5'-linked oligonucleotides tethered via nucleic bases and with opposite polarities has been performed using a modified dinucleoside bearing a phosphoramidite group at the 3'-position of one nucleoside and a dimethoxytrityl group at the 3'-position of the second nucleoside.
