1582276-54-7Relevant academic research and scientific papers
P-Chiral Phosphines Enabled by Palladium/Xiao-Phos-Catalyzed Asymmetric P-C Cross-Coupling of Secondary Phosphine Oxides and Aryl Bromides
Dai, Qiang,Li, Wenbo,Li, Zhiming,Zhang, Junliang
, p. 20556 - 20564 (2019)
The development of transition-metal-catalyzed methods for the synthesis of P-chiral phosphine derivatives poses a considerable challenge. Herein, we present a direct Pd/Xiao-Phos-catalyzed cross-coupling reaction of easily accessible secondary phosphine o
Turning regioselectivity into stereoselectivity: Efficient dual resolution of P-stereogenic phosphine oxides through bifurcation of the reaction pathway of a common intermediate
Nikitin, Kirill,Rajendran, Kamalraj V.,Mueller-Bunz, Helge,Gilheany, Declan G.
, p. 1906 - 1909 (2014/03/21)
Synthetic routes that provide facile access to either enantiomeric form of a target compound are particularly valuable. The crystallization-free dual resolution of phosphine oxides that gives highly enantioenriched materials (up to 94 % ee) in excellent y
