1582284-16-9

Basic information

• Product Name: ethyl 2-(4-phenyl-1H-1,2,3-triazol-1-yl)isonicotinate
• Synonyms: ethyl 2-(4-phenyl-1H-1,2,3-triazol-1-yl)isonicotinate
• CAS NO: 1582284-16-9
• Molecular Weight: 294.313
• Mol File: 1582284-16-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 2-(4-phenyl-1H-1,2,3-triazol-1-yl)isonicotinate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(4-phenyl-1H-1,2,3-triazol-1-yl)isonicotinate(1582284-16-9)
• EPA Substance Registry System: ethyl 2-(4-phenyl-1H-1,2,3-triazol-1-yl)isonicotinate(1582284-16-9)

Safety Data

• Hazardous Substances Data: 1582284-16-9(Hazardous Substances Data)

Upstream product

• 1582284-09-0 ethyl tetrazolo[1,5-a]pyridine-7-carboxylate 
• 536-74-3 phenylacetylene 
• 14906-37-7 ethyl isonicotinate N-oxide 

Relevant articles and documents

1,2,3-Triazol-5-ylidene bearing a pyridine auxiliary based bidentate PEPPSI type palladium(II) complex: Synthesis, structure, and application in the direct arylation of pyridine N-oxide

A novel PEPPSI (pyridine enhanced precatalyst preparation stabilization and initiation) type palladium(II) complex has been synthesized and fully characterized by NMR, HR-MS, as well as elemental analysis. The molecular structure was finally confirmed by single crystal X-ray diffraction, and it revealed that the pyridyl-armed 1,2,3-triazole ligand is coordinated to the palladium in bidentate fashion. This air and moisture insensitive complex has proven to be a suitable catalyst for the arylation of pyridine N-oxides and 2-bromopyrroles with a broad functional group tolerance, demonstrating that the robustness and high efficiency of our complex.

Conversion of pyridine N -oxides to tetrazolopyridines

An efficient and convenient procedure for the conversion of pyridine N-oxides to tetrazolopyridines by treatment with 4-toluene sulfonyl chloride and sodium azide in toluene at elevated temperature is described.