1582285-73-1Relevant academic research and scientific papers
The photocatalysis synthetic alkaloid (by machine translation)
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, (2018/11/22)
The present invention provides a catalytic synthesis method of living beings, the alkaloid comprises indole fused ring class and indole spiro compound, the process is as follows: in order to nitrogen aryl acrylamide as raw materials in under the photocatalysis with peroxide synthesis 3 - acetal 2 - indole compound, obtained through hydrolysis 3 - formyl - 2 - indole compound, further reducing synthetic alkaloid, the method routes mild, efficiency is high-efficient. The reaction in the illumination can occur under the room temperature, mild condition, has better substrate versatility and functional group tolerant. (by machine translation)
The carbomethylation of arylacrylamides leading to 3-ethyl-3-substituted indolin-2-one by cascade radical addition/cyclization
Dai, Qiang,Yu, Jintao,Jiang, Yan,Guo, Songjin,Yang, Haitao,Cheng, Jiang
supporting information, p. 3865 - 3867 (2014/04/03)
An FeCl2-promoted carbomethylation of arylacrylamides by di-tert-butyl peroxide (DTBP) is achieved, leading to 3-ethyl-3-substituted indolin-2-one in high yield. The reaction tolerates a series of functional groups, such as cyano, nitro, ethyloxy carbonyl, bromo, chloro, and trifluoromethyl groups. The radical methylation and arylation of the alkenyl group are involved in this reaction. This journal is the Partner Organisations 2014.
