158261-95-1

Basic information

• Product Name: 3-(1-PYRROLIDINYL)-1-BUTANOL
• Synonyms: 3-(1-pyrrolidinyl)-1-butanol(SALTDATA: FREE);3-Pyrrolidin-1-ylbutan-1-ol;g-Methyl-1-Pyrrolidinepropanol;3-1-pyrrolidinylbutan-1-ol;3-(1-PYRROLIDINYL)-1-BUTANOL
• CAS NO: 158261-95-1
• Molecular Formula: C8H17NO
• Molecular Weight: 143.23
• Mol File: 158261-95-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 227.924°C at 760 mmHg
• Flash Point: 96.509°C
• Appearance: /
• Density: 0.982g/cm³
• Vapor Pressure: 0.015mmHg at 25°C
• Refractive Index: 1.488
• Storage Temp.: 2-8°C
• PKA: 15.00±0.10(Predicted)
• CAS DataBase Reference: 3-(1-PYRROLIDINYL)-1-BUTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1-PYRROLIDINYL)-1-BUTANOL(158261-95-1)
• EPA Substance Registry System: 3-(1-PYRROLIDINYL)-1-BUTANOL(158261-95-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 158261-95-1(Hazardous Substances Data)

Usage

General Description

3-(1-pyrrolidinyl)-1-butanol is a chemical compound with the molecular formula C9H19NO. It is a clear, colorless liquid with a slightly sweet, floral odor and is commonly used as a fragrance ingredient in various consumer products. It is also used as a solvent for resins and as a stabilizer and fixative in perfumes, soaps, and other personal care products. In addition, it has potential applications in the pharmaceutical industry as a chiral auxiliary. The compound is considered to have low toxicity and is not known to cause any significant adverse effects on human health or the environment. However, it should be handled with care and in accordance with proper safety guidelines.

InChI:InChI=1/C8H17NO/c1-8(4-7-10)9-5-2-3-6-9/h8,10H,2-7H2,1H3

Upstream product

• 70526-06-6 (Z)-3-pyrrolidin-1-yl-but-2-enoic acid ethyl ester 
• 42980-67-6 Ethyl 3-pyrrolidinobutyrate 

Relevant articles and documents

3- Or 4-monosubstituted phenol derivatives useful as H3 ligands

The invention relates to 3- or 4-monosubstituted phenol derivatives and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. Said 3- or 4-monosubstituted phenol derivatives are H3 ligands and are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.

Chemo- and diastereoselective reduction of β-enamino esters: A convenient synthesis of both cis- and trans-γ-amino alcohols and β-amino esters

Convenient procedures for the chemo- and diastereoselective reduction of b-enamino esters 1 are described. Both cis- and trans-γ-amino alcohols 2 or b-amino esters 3 can be prepared by reduction of b-enamino esters 1, readily available starting materials, with the use of inexpensive reagents Na/i-PrOH or NaHB(OAc)3/AcOH, respectively, and the appropriate reduction conditions. The mechanisms and diastereoselectivities for the reductions are discussed. The relative configurations and conformations of the diastereoisomeric γ-amino alcohols 2 and β-amino esters 3 obtained are established by 1H and 13C NMR study and unequivocally set by their cyclic derivatives tetrahydro-1,3-oxazines 4.