15827-80-2 Usage
Uses
Used in Pharmaceutical Research:
4-Amino-3-cyano-1,2,5,6-tetrahydropyridine is utilized as a key intermediate in the synthesis of novel drugs, contributing to the development of new therapeutic agents. Its unique structure allows for the creation of diverse bioactive molecules with potential applications in treating various diseases and conditions.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 4-amino-3-cyano-1,2,5,6-tetrahydropyridine serves as a valuable building block for the synthesis of a range of bioactive compounds. Its presence in these molecules can enhance their pharmacological properties, making them more effective in treating specific medical conditions.
Used in Organic Synthesis:
4-Amino-3-cyano-1,2,5,6-tetrahydropyridine is employed as a versatile reagent in organic synthesis, enabling the creation of complex organic molecules with potential applications in various industries.
Used in Industrial Processes:
4-AMINO-3-CYANO-1,2,5,6-TETRAHYDROPYRIDINE may also have industrial uses, particularly in the production of specialty chemicals and agrochemicals, where its unique properties can contribute to the development of innovative products with specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 15827-80-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,8,2 and 7 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 15827-80:
(7*1)+(6*5)+(5*8)+(4*2)+(3*7)+(2*8)+(1*0)=122
122 % 10 = 2
So 15827-80-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H9N3/c7-3-5-4-9-2-1-6(5)8/h9H,1-2,4,8H2
15827-80-2Relevant academic research and scientific papers
Anxiolytic properties of certain annelated [1,2,3]triazolo[1,5-c]pyrimidin-5(6H)-ones
Francis,Bennett,Hyun,Rovinski,Amrick,Loo,Murphy,Neale,Wilson
, p. 2899 - 2906 (2007/10/02)
Modification of the benzodiazepine (BZ) receptor binding template 2-aryl[1,2,4]triazolo[1,5-c]quinazolin-5(6H)-one by replacement of the annelated benzene ring with various alicyclic and heterocyclic moieties led to novel structures with potent BZ receptor binding affinity. High affinity was found in some cycloalkyl-annelated [1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-ones and in some 7,8,9,10-tetrahydropyrido[3,4-e][1,2,4]triazolo[1,5-c] pyrimidin-5(6H)-ones, in which the degree of activity was strongly dependent on the N-substituent in the 9-position. Nine compounds with BZ receptor IC50 binding affinity values equal or superior to diazepam were evaluated in secondary screening. One of these, 9-benzyl-2-phenyl-7,8,9,10-tetrahydropyrido[3,4-e] [1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one, showed good activity in rats as a potential anxiolytic agent without sedative liability. However, it increased the rotorod deficit produced by ethanol at anxiolytic doses, an indication of alcohol interaction. Thus, none of the compounds showed an advantage over CGS 9896 (Yokoyama et al. J. Med. Chem. 1982, 25, 337-339), which is free of sedative and alcohol interaction potential as measured by the test procedures described.
