1582784-22-2Relevant academic research and scientific papers
N-Heterocyclic carbene-catalyzed formal cross-coupling reaction of α-haloenals with thiols: Organocatalytic construction of sp2 carbon-sulfur bonds
He, Lin,Guo, Hao,Li, Yuan-Zhen,Du, Guang-Fen,Dai, Bin
, p. 3719 - 3721 (2014)
A novel N-heterocyclic carbene (NHC)-catalyzed formal cross-coupling reaction between α-haloenals and thiols was developed. In the presence of 5 mol% NHC precursors and 1.6 equiv. potassium carbonate, various thiols coupled with α-haloenals to produce α-thioenals in 53% to 91% yield and excellent Z-selectivity. This journal is the Partner Organisations 2014.
