1583315-63-2Relevant academic research and scientific papers
4-Functionalized 1,3-diarylpyrazoles bearing benzenesulfonamide moiety as selective potent inhibitors of the tumor associated carbonic anhydrase isoforms IX and XII
Khloya, Poonam,Celik, Gulsah,Sitaram,Vullo, Daniela,Supuran, Claudiu T.,Sharma, Pawan K.
, p. 284 - 290 (2014/03/21)
A library of 4-functionalized 1,3-diarylpyrazoles (3a-3h, 5a-5g and 6a-6g) was designed, synthesized and evaluated against four human carbonic anhydrase (CA, EC 4.2.1.1) isozymes representing two cytosolic isozymes hCA I and hCA II, and two transmembrane
