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5-Hydroxy-1,4-dihydropyrimidin-4-one, also known as DHP, is a heterocyclic chemical compound belonging to the class of dihydropyrimidines. It serves as a precursor to thymidine, a nucleoside present in DNA, and features a six-membered ring structure with a hydroxyl group attached to the carbon at position 5. DHP is recognized for its potential applications in the synthesis of pharmaceuticals, agrochemicals, and as a precursor in biofuel production, along with its medicinal properties such as acting as a calcium channel blocker and inhibiting the enzyme dihydropyrimidinase.

15837-41-9

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15837-41-9 Usage

Uses

Used in Pharmaceutical Industry:
5-Hydroxy-1,4-dihydropyrimidin-4-one is used as a building block for the synthesis of pharmaceutical drugs due to its versatile chemical structure, which allows for the creation of various drug molecules with potential therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Hydroxy-1,4-dihydropyrimidin-4-one is utilized as a key component in the development of agrochemicals, contributing to the production of compounds that can enhance crop protection and yield.
Used in Biofuel Production:
5-Hydroxy-1,4-dihydropyrimidin-4-one is considered as a potential precursor in the production of biofuels, highlighting its application in the renewable energy sector and its capacity to contribute to sustainable fuel sources.
Used in Medicinal Applications:
As a calcium channel blocker, 5-Hydroxy-1,4-dihydropyrimidin-4-one is used in the treatment of various cardiovascular conditions, leveraging its ability to regulate calcium ion flow in cells.
Used in Enzyme Inhibition:
5-Hydroxy-1,4-dihydropyrimidin-4-one is employed as an inhibitor of the enzyme dihydropyrimidinase, playing a role in the metabolism of uracil and potentially influencing pyrimidine synthesis and degradation pathways in biological systems.

Check Digit Verification of cas no

The CAS Registry Mumber 15837-41-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,8,3 and 7 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 15837-41:
(7*1)+(6*5)+(5*8)+(4*3)+(3*7)+(2*4)+(1*1)=119
119 % 10 = 9
So 15837-41-9 is a valid CAS Registry Number.
InChI:InChI=1/C4H4N2O2/c7-3-1-5-2-6-4(3)8/h1-2,7H,(H,5,6,8)

15837-41-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Hydroxypyrimidin-4(3H)-one

1.2 Other means of identification

Product number -
Other names 5-Hydroxypyrimidin-4(1H)-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15837-41-9 SDS

15837-41-9Downstream Products

15837-41-9Relevant academic research and scientific papers

An autoxidation study of C2 substituted pyrimidine amino reductones

Ta-Shma, Rachel,Torres, Avital,Chevion, Mordechai,Breuer, Eli,Quntar, Abed Al Aziz,Enk, Claes D.,Srebnik, Morris

, p. 5469 - 5473 (2006)

Three pyrimidine derivatives (8a-c), differing from isouramil and divicine at C2, have been synthesized and their autoxidation rates measured spectrophotometrically. The autoxidation rates of all five pyrimidines (8a-c, isouramil and divicine) were correl

SUBSTITUTED PYRIMIDINES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS EFFECTIVE ABSORBENTS OF UV IRRADIATION

-

Page/Page column 11; 14, (2010/11/28)

The present invention discloses substituted pyrimidines, processes for their synthesis and their use as effective sun-protecting agents either alone or in combination with other known sun-protecting agents.

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