158388-57-9

Basic information

• Product Name: benzylidene-1-(4-trifluoromethylphenyl)-2,2,2-trifluoroethylamine
• Synonyms: benzylidene-1-(4-trifluoromethylphenyl)-2,2,2-trifluoroethylamine
• CAS NO: 158388-57-9
• Molecular Weight: 331.26
• Mol File: 158388-57-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzylidene-1-(4-trifluoromethylphenyl)-2,2,2-trifluoroethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: benzylidene-1-(4-trifluoromethylphenyl)-2,2,2-trifluoroethylamine(158388-57-9)
• EPA Substance Registry System: benzylidene-1-(4-trifluoromethylphenyl)-2,2,2-trifluoroethylamine(158388-57-9)

Safety Data

• Hazardous Substances Data: 158388-57-9(Hazardous Substances Data)

Upstream product

• 74853-66-0 4'-trifluoromethyl-2,2,2-trifluoroacetophenone 
• 100-46-9 benzylamine 

Relevant articles and documents

Thermocontrolled benzylimine-benzaldimine rearrangement over Nafion-H catalysts for efficient entry into α-trifluoromethylbenzylamines

Nafion-H and Nafion SAC-13 are efficient solid Br?nsted acid catalysts for the preparation of trifluoromethyl ketimines from benzylamines and trifluoromethylated ketones in high yields. A finely tuned benzylimine- benzaldimine rearrangement by facile 1,3-hydrogen shift has been achieved for the formation of fluorinated benzaldimines in high yields by careful optimization of reaction conditions including attempts under microwave conditions and a flow system. These α-trifluoromethylated benzaldimines are efficient precursors for pharmaceutically important α- trifluoromethylated benzylamines, accessed through their direct acid hydrolysis.