158398-81-3

Upstream product

• 115170-26-8 4-methoxy-5,8-quinolinedione 
• 283152-31-8 4-(2-nitrophenyl)-1-(dimethylamino)-1-aza-1,3-butadiene 
• 212393-97-0 7-bromo-4-methoxy-5,8-quinolinedione 
• 1466-88-2 2-nitrocinnamic aldehyde 

Downstream Products

• 129722-90-3 meridine 
• 158398-82-4 4-methoxy-6-(2'-nitrophenyl)pyrido[3,2-g]quinoline-5,10-dione 

Relevant academic research and scientific papers

Synthesis of meridine, a pentacyclic aza-aromatic alkaloid

A pentacyclic aza-aromatic alkaloid, meridine (1), was synthesized from 4- methoxy-5,8-quinolinedione (4) and o-nitrocinnamaldehyde N,N- dimethylhydrazone (5) in four steps.

Synthesis of meridine, cystodamine, and related compounds including iminoquinolinequinone structure

Two aromatic alkaloids, meridine (1) and cystodamine (3), and related compounds (2, 4, 5) were synthesized by hetero Diels-Alder reaction between 4-methoxy- (or 4-chloro-)5,8-quinolinedione and 2-nitrocinnamaldehyde dimethylhydrazone.