158469-75-1Relevant articles and documents
EPC-Synthesis of (S)-3-Hydroxy-3-mercaptomethylquinuclidine, a Chiral Building Block for the Synthesis of the Muscarinic Agonist AF 102B
Boes, Michael,Canesso, Rolf
, p. 1889 - 1896 (2007/10/02)
The catalytic modification of the Sharpless-epoxidation reaction was employed in a short EPC-synthesis of the title compound.The asymmetric epoxidation of the allylic alcohol (6) proceeded in 75percent yield and 94percent enantiomeric excess.In a 4 step s