1584705-47-4Relevant academic research and scientific papers
Synthesis of pyrroles from terminal alkynes, N-sulfonyl azides, and alkenyl alkyl ethers through 1-sulfonyl-1,2,3-triazoles
Kim, Cheol-Eui,Park, Sangjune,Eom, Dahan,Seo, Boram,Lee, Phil Ho
supporting information, p. 1900 - 1903 (2014/05/06)
A method for synthesis of substituted pyrroles has been developed. 1-Sulfonyl-1,2,3-triazoles generated from terminal alkynes gave α-imino rhodium carbene complexes, which when reacted with alkenyl alkyl ethers afforded substituted pyrroles. The method can be efficiently applied to a one-pot sequential reaction starting from terminal alkynes.
Rhodium-catalyzed transannulation of 1,2,3-triazoles to polysubstituted pyrroles
Rajasekar, Shanmugam,Anbarasan, Pazhamalai
supporting information, p. 8428 - 8434 (2015/03/18)
Rhodium-catalyzed transannulation of N-sulfonyl-1,2,3-triazoles with vinyl ether has been accomplished for the synthesis of various polysubstituted pyrroles. The present method allows the synthesis of mono-, di-, and trisubstituted pyrroles with appropriate substitutions. Furthermore, the developed methodology was applied in the formal synthesis of neolamellarin A, an antitumor agent.
Facile synthesis of pyrroles via Rh(II)-catalyzed transannulation of 1-tosyl-1,2,3-triazoles with silyl or alkyl enol ethers
Feng, Juan,Wang, Yuanhao,Li, Qingong,Jiang, Renwang,Tang, Yefeng
, p. 6455 - 6458 (2014/12/11)
A novel Rh(II)-catalyzed transannulation of 1-tosyl-1,2,3-triazoles with silyl or alkyl enol ethers has been developed, which enables the facile synthesis of substituted pyrroles in a regiocontrollable manner. Moreover, the methodology could be extended to access 3-pyrrolin-2-one derivatives with silyl ketene acetals used as the reaction partner.
