1585223-50-2

Basic information

• Product Name: ethyl 7-bromo-3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-1H-indole-2-carboxylate
• Synonyms: ethyl 7-bromo-3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-1H-indole-2-carboxylate
• CAS NO: 1585223-50-2
• Molecular Weight: 464.787
• Mol File: 1585223-50-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 7-bromo-3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-1H-indole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 7-bromo-3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-1H-indole-2-carboxylate(1585223-50-2)
• EPA Substance Registry System: ethyl 7-bromo-3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-1H-indole-2-carboxylate(1585223-50-2)

Safety Data

• Hazardous Substances Data: 1585223-50-2(Hazardous Substances Data)

Downstream Products

• 1585223-58-0 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-7-(furan-2-yl)-1H-indole-2-carboxylic acid 
• 1585223-56-8 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-7-(furan-2-yl)-N-(phenylsulfonyl)-1H-indole-2-carboxamide 
• 1585223-57-9 ethyl 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-7-(furan-2-yl)-1H-indole-2-carboxylate 
• 1585223-53-5 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-7-(o-tolyl)-1H-indole-2-carboxylic acid 
• 1585223-52-4 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-N-(methylsulfonyl)-7-(o-tolyl)-1H-indole-2-carboxamide 
• 1585223-66-0 ethyl 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-7-(4-methylpyridin-3-yl)-1H-indole-2-carboxylate 
• 1585223-78-4 ethyl 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-7-(pyridin-3-yl)-1H-indole-2-carboxylate 
• 1585227-14-0 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-7-(3,5-dimethyl-1H-pyrazol-4-yl)-N-(phenylsulfonyl)-1H-indole-2-carboxamide 
• 1585223-89-7 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-7-(2-methylpyridin-3-yl)-N-(phenylsulfonyl)-1H-indole-2-carboxamide 
• 1585223-65-9 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-7-(4-methylpyridin-3-yl)-N-(phenylsulfonyl)-1H-indole-2-carboxamide 
• 1585223-77-3 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-N-(phenylsulfonyl)-7-(pyridin-3-yl)-1H-indole-2-carboxamide 
• 1585223-67-1 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-7-(4-methylpyridin-3-yl)-1H-indole-2-carboxylic acid 
• 1585223-79-5 3-(3-(4-chloro-3,5-dimethylphenoxy)propyl)-7-(pyridin-3-yl)-1H-indole-2-carboxylic acid 

Relevant articles and documents

SUBSTITUTED INDOLE MCL-1 INHIBITORS

The present invention provides for compounds that inhibit the activity of an anti-apoptotic Bcl-2 family member Myeloid cell leukemia-1 (Mcl-1) protein. The present invention also provides for pharmaceutical compositions as well as methods for using compounds for treatment of diseases and conditions (e.g., cancer) characterized by the over-expression or dysregulation of Mcl-1 protein.