158530-79-1Relevant academic research and scientific papers
SYNTHESIS OF SUBSTITUTED HETEROCYCLES. SIMPLE METHOD FOR THE INTRODUCTION OF THE N-HYDROXYUREA FUNCTIONALITY
Ku, Yi-Yin,Patel, Ramesh R.,Roden, Brian A.,Sawick, David P.
, p. 6017 - 6020 (2007/10/02)
A simple method for the introduction of the N-hydroxyurea functionality has been developed.This involves conjugate addition of hydroxylamine to a vinylsulfone substrate.This method was successfully used in a facile synthesis of the 5-lipoxygenase inhibitors, zileuton and A-69412.
