158583-66-5Relevant articles and documents
Potential Antimalarials. XXI Mannich Base Derivatives of 4-phenols
Barlin, Gordon B.,Ireland, Stephen J.,Nguyen, Trang M. T.,Kotecka, Barbara,Rieckmann, Karl H.
, p. 1553 - 1560 (2007/10/02)
Syntheses are reported for 4-(7-chloroquinolin-4-ylamino)-2,6-bis(piperidin-1-ylmethyl)phenol (2) and its 3-fluoro and 3-piperidinyl derivatives.Some mono-Mannich analogues with 2-fluoro, 2-t-butyl and 3-trifluoromethyl substituents have also been prepare