1585970-78-0

Basic information

• Product Name: (R)-N-((S)-2-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-4-(3,5-dimethylisoxazol-4-yl)-4-oxobutan-2-yl)-2-methylpropane-2-sulfinamide
• Synonyms: (R)-N-((S)-2-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-4-(3,5-dimethylisoxazol-4-yl)-4-oxobutan-2-yl)-2-methylpropane-2-sulfinamide
• CAS NO: 1585970-78-0
• Molecular Weight: 476.547
• Mol File: 1585970-78-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-N-((S)-2-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-4-(3,5-dimethylisoxazol-4-yl)-4-oxobutan-2-yl)-2-methylpropane-2-sulfinamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-((S)-2-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-4-(3,5-dimethylisoxazol-4-yl)-4-oxobutan-2-yl)-2-methylpropane-2-sulfinamide(1585970-78-0)
• EPA Substance Registry System: (R)-N-((S)-2-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-4-(3,5-dimethylisoxazol-4-yl)-4-oxobutan-2-yl)-2-methylpropane-2-sulfinamide(1585970-78-0)

Safety Data

• Hazardous Substances Data: 1585970-78-0(Hazardous Substances Data)

Upstream product

• 1616105-35-1 1-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)ethanone 
• 1616100-67-4 1-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)ethanol 
• 35166-20-2 1-(3,5-dimethyl-1,2-oxazol-4-yl)ethanone 
• 1585971-39-6 (R,E)-N-(1-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)ethylidene)-2-methylpropane-2-sulfinamide 
• 2510-36-3 3,5-dimethyl-4-isoxazolecarboxylic acid 
• 1223452-45-6 N-methoxy-N-methyl-3,5-dimethylisoxazole-4-carboxamide 
• 473416-91-0 5-bromo-2,4-difluorobenzaldehyde 
• 348-57-2 2,4-difluorobromobenzene 
• 28342-75-8 1,5-dibromo-2,4-difluorobenzene 
• 1415208-99-9 2,4-difluoro-5-(pyrimidin-5-yl)benzaldehyde 

Downstream Products

• 1616100-68-5 (R)-N-((2S,4R)-2-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-4-(3,5-dimethylisoxazol-4-yl)-4-hydroxybutan-2-yl)-2-methylpropane-2-sulfinamide 
• 1616100-69-6 (1R,3S)-3-amino-3-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-1-(3,5-dimethylisoxazol-4-yl)butan-1-ol 
• 1616100-70-9 N-(((2S,4R)-2-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-4-(3,5-dimethylisoxazol-4-yl)-4-hydroxybutan-2-yl)carbamothioyl)benzamide 
• 1616100-22-1 (4S,6S)-4-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-6-(3,5-dimethylisoxazol-4-yl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine 

Relevant articles and documents

Synthesis of β-disubstituted β-amino isoxazolyl ketones by addition of ketimines with isoxazolyl methyl ketone enolates

A series of β-disubstituted N-sulfinyl β-amino isoxazolyl ketones has been prepared by addition of tert-butanesulfinyl ketimines with the n-BuLi-generated enolates of isoxazolyl methyl ketones.

Synthesis of β-disubstituted β-amino isoxazolyl ketones by addition of ketimines with isoxazolyl methyl ketone enolates

A series of β-disubstituted N-sulfinyl β-amino isoxazolyl ketones has been prepared by addition of tert-butanesulfinyl ketimines with the n-BuLi-generated enolates of isoxazolyl methyl ketones.