1585988-05-1Relevant articles and documents
Iodine-Catalyzed Odorless Synthesis of S-Thiocarbamates with Sulfonyl Chlorides as a Sulfur Source
Bao, Wen-Hu,He, Min,Wang, Jing-Ting,Peng, Xin,Sung, Men,Tang, Zilong,Jiang, Si,Cao, Zhong,He, Wei-Min
, p. 6065 - 6071 (2019)
A general and efficient protocol for the direct preparation of various S-thiocarbamates with readily available and inexpensive sulfonyl chlorides as an odorless sulfur source was developed. The employment of easily available reactants, excellent functiona
Mild oxidation of tosylmethylisocyanide to tosylmethylisocyanate: Utility in synthetic and medicinal chemistry
Le, Hoang V.,Ganem, Bruce
, p. 2003 - 2005 (2014/04/03)
A convenient and efficient (one-step) oxidation is reported of commercially available tosylmethylisocyanide (TOSMIC) to form tosylmethylisocyanate, making this highly reactive bifunctional molecule a readily available synthetic reagent. Besides engaging in nucleophilic addition reactions with alcohols, amines, and thiols, tosylmethylisocyanate also reacts with carboxylic acids to form tosylmethylamides, which undergo substitution reactions in the presence of organocopper and organomagnesium reagents.