1586039-41-9

Basic information

• Product Name: 5-amino-N-(5-(6-azido-4,4-difluorooxepan-2-yl)-1-methyl-1H-pyrazol-4-yl)-2-(2,6-difluorophenyl)thiazole-4-carboxamide
• Synonyms: 5-amino-N-(5-(6-azido-4,4-difluorooxepan-2-yl)-1-methyl-1H-pyrazol-4-yl)-2-(2,6-difluorophenyl)thiazole-4-carboxamide
• CAS NO: 1586039-41-9
• Molecular Weight: 510.475
• Mol File: 1586039-41-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-amino-N-(5-(6-azido-4,4-difluorooxepan-2-yl)-1-methyl-1H-pyrazol-4-yl)-2-(2,6-difluorophenyl)thiazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-N-(5-(6-azido-4,4-difluorooxepan-2-yl)-1-methyl-1H-pyrazol-4-yl)-2-(2,6-difluorophenyl)thiazole-4-carboxamide(1586039-41-9)
• EPA Substance Registry System: 5-amino-N-(5-(6-azido-4,4-difluorooxepan-2-yl)-1-methyl-1H-pyrazol-4-yl)-2-(2,6-difluorophenyl)thiazole-4-carboxamide(1586039-41-9)

Safety Data

• Hazardous Substances Data: 1586039-41-9(Hazardous Substances Data)

Upstream product

• 1270034-25-7 5-[(tert-butoxycarbonyl)amino]-2-(2,6-difluorophenyl)-1,3-thiazole-4-carboxylic acid 
• 1187056-40-1 5-amino-2-(2,6-difluorophenyl)-1,3-thiazole-4-carboxylic acid 
• 71760-04-8 propylphosphonic anhydride 

Relevant articles and documents

CYCLIC ETHER PYRAZOL-4-YL-HETEROCYCLYL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE

Cyclic ether pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein R2 is a cyclic ether and X is thiazolyl, pyrazinyl, pyridinyl, or pyrimidinyl, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.