15863-18-0

Basic information

• Product Name: Thiourea, N-(1-methylethyl)-N'-(4-methylphenyl)-
• Synonyms: N-isopropyl-N'-(4-methylphenyl)thiourea
• CAS NO: 15863-18-0
• Molecular Formula: C₁₁H₁₆N₂S
• Molecular Weight: 208.32314
• Mol File: 15863-18-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Thiourea, N-(1-methylethyl)-N'-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiourea, N-(1-methylethyl)-N'-(4-methylphenyl)-(15863-18-0)
• EPA Substance Registry System: Thiourea, N-(1-methylethyl)-N'-(4-methylphenyl)-(15863-18-0)

Safety Data

• Hazardous Substances Data: 15863-18-0(Hazardous Substances Data)

Upstream product

• 75-31-0 isopropylamine 
• 622-59-3 1-isothiocyanato-4-methylbenzene 

Downstream Products

• 90140-37-7 isopropyl(4-methylphenyl)carbodiimide 
• 129226-18-2 5-[(E)-Isopropylimino]-4-p-tolyl-4,5-dihydro-[1,2,4]thiadiazol-3-ylamine 
• 90140-42-4 1,2,7,7a-Tetrahydro-1-methyl-2-(methylimino)-7-(4-methylphenyl)-4,7a-diphenylpyrrolo<2,3-d><1,3>oxazin-5,6-dion 
• 90140-28-6 4-<α-(4-Methylphenylimino)benzyl>-5-phenyl-2,3-furandion 

Relevant articles and documents

Site-Selective Deoxygenative Amination of Azine N-Oxides with Carbodiimides under Catalyst-, Activator-, Base-, and Solvent-Free Conditions

An operationally simple method for synthesizing 2-amino azines via [3+2] dipolar cycloaddition of azine N-oxide with carbodiimide has been demonstrated. The reaction can proceed smoothly under simple heating conditions without any transition metal catalyst, activator, base, and solvent. This transformation demonstrates a broad substrate scope and produces CO2 as the only co-product. The applicability of this method is highlighted by the late-stage modification of bioactive molecules, including quinine, (±)-α-tocopherol, and tryptamine modified quinoline.