15863-22-6

Usage

Chemical class

Thiourea derivative

Cyclohexyl group

A six-membered ring of carbon and hydrogen atoms

4-Methoxyphenyl group

A phenyl group (six-membered ring of carbon and hydrogen atoms) with a methoxy group (-OCH3) attached to the fourth carbon

Anti-inflammatory

Reduces inflammation in the body

Anti-nociceptive

Relieves pain

Anti-tumor

Inhibits the growth of tumors

Anti-cancer agent

Used in the treatment of cancer

Anti-viral agent

Used to combat viral infections

Research significance

Promising candidate for further research and pharmaceutical applications due to its structure and properties

Upstream product

• 108-91-8 cyclohexylamine 
• 2284-20-0 4-Methoxyphenyl isothiocyanate 

Downstream Products

• 121577-74-0 Cyclohexyl-(4-methoxy-phenyl)-carbodiimide 
• 1019107-96-0 3-cyclohexyl-1-(4-methoxyphenyl)-5-[(E)-1-phenylmethylidene]-2-thioxoimidazolidin-4-one 
• 1394822-75-3 (Z)-4-methoxyphenyl N-cyclohexyl-N'-(4-methoxyphenyl)carbamimidate 
• 130255-95-7 5-[(Z)-Cyclohexylimino]-4-(4-methoxy-phenyl)-[1,2,4]dithiazolidin-3-one 
• 130256-07-4 2-Cyclohexyl-4-(4-methoxy-phenyl)-3-thioxo-[1,2,4]thiadiazolidin-5-one 
• 39964-59-5 [2-cyclohexylimino-3-(4-methoxy-phenyl)-4-oxo-thiazolidin-5-yl]-acetic acid 

Relevant academic research and scientific papers

Nickle Catalysis Enables Access to Thiazolidines from Thioureas via Oxidative Double Isocyanide Insertion Reactions

An efficient synthesis of thiazolidine-2,4,5-triimine derivatives was developed via Ni-catalyzed oxidative double isocyanide insertion to thioureas under air conditions, in which thioureas play three roles as a substrate, a ligand, and overcoming isocyanide polymerization. The reaction is featured by employing a low-cost and low loading Ni(acac)2 catalyst, without any additives, and high atom economy. This is the first example to directly apply a Ni(II) catalyst in oxidative double isocyanide insertion reactions.

The HgCl2-promoted guanylation reaction: The scope and limitations

The HgCl2-promoted guanylation reaction was studied with various substituted thiourea starting materials and the scope and limitations are presented. The process was found to be effective with thioureas containing at least one N-conjugated subs