158634-64-1

Basic information

• Product Name: 4-ethoxy-N-[(E)-(4-methylphenyl)methylidene]aniline
• Synonyms: 4-Ethoxy-N-[(E)-(4-methylphenyl)methylene]aniline; benzenamine, 4-ethoxy-N-[(1E)-(4-methylphenyl)methylene]-; p-methylbenzylidene-(4-ethoxyphenyl)-amine
• CAS NO: 158634-64-1
• Molecular Formula: C₁₆H₁₇NO
• Molecular Weight: 239.3123
• Mol File: 158634-64-1.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 379.2°C at 760 mmHg
• Flash Point: 148.4°C
• Density: 0.98g/cm³
• Vapor Pressure: 1.3E-05mmHg at 25°C
• Refractive Index: 1.532
• CAS DataBase Reference: 4-ethoxy-N-[(E)-(4-methylphenyl)methylidene]aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ethoxy-N-[(E)-(4-methylphenyl)methylidene]aniline(158634-64-1)
• EPA Substance Registry System: 4-ethoxy-N-[(E)-(4-methylphenyl)methylidene]aniline(158634-64-1)

Safety Data

• Hazardous Substances Data: 158634-64-1(Hazardous Substances Data)

Upstream product

• 589-18-4 4-Methylbenzyl alcohol 
• 156-43-4 4-Ethoxyaniline 
• 104-87-0 4-methyl-benzaldehyde 

Relevant articles and documents

Synthesis of-lactams from acids and imines using thiocarbonyldiimidazole

Thiocarbonyldiimidazole has been found to be an efficient acid activator for the synthesis of-lactams by ketene-imine cycloaddition at room temperature. The experimental procedure is simple and results in excellent yields of the products. All products wer

Synthesis of structurally diverse 2-azetidinones via staudinger reaction on a solid support

Trimellitic anhydride was attached to Merrifield resin and a ketene was generated from polymer-bound phthaloylglycine. Then this polymer reacted with imines in the presence of Vilsmeier reagent and triethylamine to afford the solid-phase-tethered β-lactam products. Selective cleavage of supported β-lactams by trifluoroacetic acid and methylhydrazine gave 4-carboxyphthalimido- and 3-amino-β-lactams, respectively. The trans-stereochemistry was found in all products.

The Vilsmeier reagent: a useful and versatile reagent for the synthesis of 2-azetidinones

(Chloromethylene)dimethylammonium chloride (Vilsmeier reagent), prepared easily from N,N-dimethylformamide and oxalyl chloride or thionyl chloride, works as a versatile acid activator reagent for the direct [2+2] ketene-imine cycloaddition of substituted