158670-19-0

Basic information

• Product Name: 3-{4-nitrophenyl}indolizine-1-carbonitrile
• Synonyms: 3-{4-nitrophenyl}indolizine-1-carbonitrile
• CAS NO: 158670-19-0
• Molecular Formula: C15H9N3O2
• Molecular Weight: 263.25086
• Mol File: 158670-19-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-{4-nitrophenyl}indolizine-1-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{4-nitrophenyl}indolizine-1-carbonitrile(158670-19-0)
• EPA Substance Registry System: 3-{4-nitrophenyl}indolizine-1-carbonitrile(158670-19-0)

Safety Data

• Hazardous Substances Data: 158670-19-0(Hazardous Substances Data)

Upstream product

• 110-86-1 pyridine 
• 920-37-6 2-Chloroacrylonitrile 
• 39184-67-3 3-chloro-3-(p-nitrophenyl)diazirine 
• 122277-66-1 4-nitrophenylchloropyridinium ylide 
• 2937-05-5 4-nitrobenzenesulfonohydrazide 
• 3352-05-4 indolizine-1-carbonitrile 
• 15959-31-6 sodium 4-nitrobenzenesulfinate 

Relevant articles and documents

Palladium-catalyzed C-3 desulfitative arylation of indolizines with sodium arylsulfinates and arylsulfonyl hydrazides

Derivatized indolizines were efficiently prepared by direct C-3 arylation of indolizines using sodium arylsulfinates and arylsulfonyl hydrazides. Pd-catalyzed desulfitative C-3 arylation with sodium arylsulfinates was achieved with the assistance of peroxides, and the catalytic efficiency was promoted by N-containing ligands. Arylsulfonyl hydrazides were also successfully applied in Pd-catalyzed desulfitative C-3 arylation with indolizines, and the side homocoupling reactions can be restrained in the component solvent under milder conditions. Various derivatives were synthesized in good yields by both methods, offering expedient protocols for the synthesis of C-3 functionalized indolizine molecules.