1586781-78-3Relevant articles and documents
Convenient synthesis of monobenzylated hydrazides via aqueous zinc-mediated addition reactions
Breton, Gary W.
supporting information, p. 1128 - 1136 (2014/04/03)
Addition of substituted benzyl bromides to dialkyl azodicarboxylates under aqueous zinc-mediated addition conditions occurs readily to afford monobenzylated hydrazides in good to excellent yields. The reaction is tolerant of a variety of substituents on the benzyl bromide ring. Several dialkyl azodicarboxylates were successfully tested under the reaction conditions. The limitations of the reaction are also addressed.