1586782-24-2

Upstream product

• 208715-13-3 C₁₈H₂₂N₂O₅ 
• 58610-65-4 ethyl 2-(6′-cyan-5′-oxo-3′,5′-dihydro-2′H-spiro[[1,3]dioxolane-2,1′-indolizine]-7′-yl)acetate 
• 1586782-21-9 C₂₃H₂₄N₂O₅ 
• 108-24-7 acetic anhydride 
• 620-05-3 iodomethylbenzene 
• 17376-04-4 2-phenethyl iodide 

Downstream Products

• 1586782-27-5 C₂₅H₂₉NO₇ 
• 1586781-85-2 C₂₁H₂₁NO₅ 
• 1586781-89-6 C₂₁H₂₁NO₆ 

Relevant academic research and scientific papers

Asymmetric a-hydroxylation of a lactone with vinylogous pyridone by using a guanidine-urea bifunctional organocatalyst: Catalytic enantioselective synthesis of a key intermediate for (20S)-camptothecin analogues

We have developed a catalytic asymmetric synthesis of (S)-4-ethyl-6,6- (ethylenedioxy)-7,8-dihydro-4-hydroxy- 1H-pyrano[3,4-f]indolizine-3,10(4H)dione (5a), a synthetic intermediate for (20S)-camptothecin analogues. A key step in this synthesis is an asym