158688-63-2

Basic information

• Product Name: 4-AMino-1-phenyl-1H-iMidazole HCl
• Synonyms: 4-AMino-1-phenyl-1H-iMidazole HCl;1-phenyl-1H-iMidazol-4-aMine;1-phenyl-1H-iMidazol-4-aMine hydrochloride
• CAS NO: 158688-63-2
• Molecular Formula: C₉H₉N₃
• Molecular Weight: 195.6488
• Mol File: 158688-63-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 4-AMino-1-phenyl-1H-iMidazole HCl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMino-1-phenyl-1H-iMidazole HCl(158688-63-2)
• EPA Substance Registry System: 4-AMino-1-phenyl-1H-iMidazole HCl(158688-63-2)

Safety Data

• Hazardous Substances Data: 158688-63-2(Hazardous Substances Data)

Usage

General Description

4-Amino-1-phenyl-1H-imidazole HCl is a chemical compound with both a phenyl group and an imidazole ring. It is also known as N-(4-imidazolyl)aniline hydrochloride and is used in pharmaceutical research and development for its potential antiviral and antifungal properties. 4-AMino-1-phenyl-1H-iMidazole HCl may also be used in the synthesis of other pharmaceuticals. 4-Amino-1-phenyl-1H-imidazole HCl is a white to off-white solid and is typically handled and stored under recommended safety precautions due to its potential to cause irritation and harm if not handled properly.

Upstream product

• 41384-83-2 1-phenyl-4-nitro-1H-imidazole 
• 98-80-6 phenylboronic acid 

Downstream Products

• 1178533-25-9 1-phenyl-5-(2-thienyl)-7-(trifluoromethyl)-1H-imidazo[4,5-b]pyridine 
• 1178533-24-8 5-methyl-1-phenyl-7-(trifluoromethyl)-1H-imidazo[4,5-b]pyridine 
• 268538-46-1 phenyl (1-phenyl-1H-imidazol-4-yl)carbamate 
• 90946-05-7 N-(1-phenyl-1H-imidazol-4-yl)-formamide 
• 83325-36-4 N-(1-phenyl-1H-imidazol-4-yl)-acetamide 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY

This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that inhibit (e.g., antagonize) Stimulator of Interferon Genes (STING). Said chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.

CYANO-SUBSTITUTED HETEROCYCLES WITH ACTIVITY AS INHIBITORS OF USP30

The present invention relates to cyano-substituted-heterocycles of Formula (I) with activity as inhibitors of deubiquitilating enzymes, in particular, ubiquitin C-terminal hydrolase 30 or ubiquitin specific peptidase 30 (USP30), having utility in a variety of therapeutic areas including cancer and conditions involving mitochondrial dysfunction. (Formula (I))

Facile synthesis of fluorinated 1-desazapurines

A preparative approach towards 1-desazapurines, starting from 4(5)-aminoimidazoles and polyfluoroalkyl-containing 1,3-CCC-biselectrophiles was developed. As a result, a set of fluorinated 1-desazapurines was synthesized. Additionally, a synthetic route to 1-desazapurines bearing a sugar-mimicking group is proposed. Georg Thieme Verlag Stuttgart.