158692-25-2

Upstream product

• 2861-28-1 1,3-benzodioxole-5-acetic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 158692-26-3 4-(1-carbomethoxy-1-(3,4-methylenedioxy phenyl)methoxy)-3,5-dipropylbenzylalcohol 
• 159591-47-6 methyl α-(4-hydroxymethyl-2-n-propyl-phenoxy)-3,4-methylenedioxyphenylacetate 
• 177952-86-2 methyl α-(2-n-propyl-4-cyanophenoxy)-3,4-methylenedioxyphenylacetate 
• 159591-58-9 methyl α-(2-n-propyl-4-aminosulfonyl-phenoxy)-3,4-methylenedioxyphenylacetate 
• 161921-84-2 methyl 2-(2-chloro-4-hydroxymethyl-6-propylphenoxy)-2-(3,4-methylenedioxyphenyl)acetate 

Relevant academic research and scientific papers

BENZIMIDAZOLINONES SUBSTITUTED WITH PHENOXYPHENYLACETIC ACID DERIVATIVES

Phenoxyphenylacetic acids and derivatives of the general structural formula I STR1 have endothelin antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, pulmonary hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, endotoxic shock, inflammatory diseases including Raynaud's disease and asthma.

Six-membered ring fused imidazoles substituted with phenoxyphenylacetic acid derivatives

Phenoxyphenylacetic acids and derivatives of general structural formula I have endothelin STR1 antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, congestive heart failure, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, inflammatory diseases, Raynaud's disease, and endotoxic shock, and asthma.