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158727-56-1

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158727-56-1 Usage

General Description

2-Methoxy-4-(trifluoromethyl)aniline is a chemical compound with the molecular formula C8H8F3NO. It is an aromatic amine with a methoxy group and a trifluoromethyl group attached to the benzene ring. 2-METHOXY-4-(TRIFLUOROMETHYL)ANILINE is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a building block for the preparation of dyes, pigments, and polymers. The trifluoromethyl group in the molecule is known to enhance the biological activity of certain compounds, making this chemical an important building block in medicinal chemistry research. Additionally, it can be used as a reagent in organic synthesis and as a UV absorber in certain applications. However, it is important to handle this compound with care due to its potential hazards such as skin and eye irritation and harmful effects if ingested or inhaled.

Check Digit Verification of cas no

The CAS Registry Mumber 158727-56-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,8,7,2 and 7 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 158727-56:
(8*1)+(7*5)+(6*8)+(5*7)+(4*2)+(3*7)+(2*5)+(1*6)=171
171 % 10 = 1
So 158727-56-1 is a valid CAS Registry Number.

158727-56-1 Well-known Company Product Price

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  • Aldrich

  • (JWP00404)  2-Methoxy-4-trifluoromethyl-aniline  AldrichCPR

  • 158727-56-1

  • JWP00404-1G

  • 4,832.10CNY

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158727-56-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Methoxy-4-(trifluoromethyl)aniline

1.2 Other means of identification

Product number -
Other names PC4598

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:158727-56-1 SDS

158727-56-1Relevant articles and documents

Vapochromic Luminescent π-Conjugated Systems with Reversible Coordination-Number Control of Hypervalent Tin(IV)-Fused Azobenzene Complexes

Gon, Masayuki,Tanaka, Kazuo,Chujo, Yoshiki

, p. 7561 - 7571 (2021)

The dynamic and reversible changes of coordination numbers between five and six in solution and solid states, based on hypervalent tin(IV)-fused azobenzene (TAz) complexes, are reported. It was found that the TAz complexes showed deep-red emission owing t

QUINOLINONE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS

-

, (2021/12/31)

Disclosed herein are certain quinolinone derivatives of Formula (A) that are methionine adenosyltransferase 2A (MAT2A) inhibitors. Also disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of MAT2A such as cancer, including cancers characterized by reduced or absence of methylthioadenosine phosphorylase (MTAP) activity.

Nickel-Catalyzed Direct C-H Trifluoromethylation of Free Anilines with Togni's Reagent

Gao, Xianying,Geng, Yang,Han, Shuaijun,Liang, Apeng,Li, Jingya,Zou, Dapeng,Wu, Yusheng,Wu, Yangjie

supporting information, p. 3732 - 3735 (2018/07/22)

An efficient nickel-catalyzed C-H trifluoromethylation for the synthesis of trifluoromethylated free anilines using Togni's reagent has been developed. This approach exhibits a good functional group tolerance, good regioselectivity, and chemoselectivity under mild conditions. The newly developed economical one-step method is a better alternative to synthesize trifluoromethylated free anilines.

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