158750-41-5Relevant academic research and scientific papers
Synthesis of cyclic oligopeptides containing an Arg-Gly-Asp (RGD) sequence
Sofuku, Shosuke,Hoshida, Akiko,Shimada, Takehiro,Takada, Yoichi,Takakuwa, Takashi
, p. 1799 - 1801 (2007/10/03)
The synthesis of cyclic RGD peptides with 8 - 10 residues cyclized by an amide bond and the relationship between their structure and activity (i.e. circular dichroism spectrum and inhibition of platelet aggregation) are reported. The linear peptides were
Synthesis and NMR studies of RGDSPASS-containing cystine peptides
Yamamoto,Sofuku
, p. 2167 - 2175 (2007/10/02)
Three types of Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser (RGDSPASS)-containing cystine peptides, FR-1, FR-2, and FR-3, were designed and synthesized. These cyclic peptides exhibited high activities as a platelet aggregation inhibitor. Using rabbit platelet-rich pla
