1587691-64-2Relevant academic research and scientific papers
Fe-catalyzed novel domino isomerization/cyclodehydration of substituted 2-[(indoline-3-ylidene)(methyl)]benzaldehyde derivatives: An efficient approach toward benzo[ b ]carbazole derivatives
Paul, Kartick,Bera, Krishnendu,Jalal, Swapnadeep,Sarkar, Soumen,Jana, Umasish
, p. 2166 - 2169 (2014/05/06)
A new and efficient protocol to synthesize substituted benzo[b]carbazole derivatives has been demonstrated involving iron-catalyzed domino isomerization/cyclodehydration sequences from substituted 2-[(indoline-3- ylidene)(methyl)]benzaldehyde derivatives. The substrates could be easily made via Pd-catalyzed domino Heck-Suzuki coupling from 2-bromo-N-propargylanilide derivatives in high yields. Notably, the generality and efficiency of this two-stage domino strategy was further exemplified by the synthesis of a polycyclic benzofuran derivative.
