1587692-61-2

Basic information

• Product Name: ethyl 4-bromo-2-formyl-3-(4-methoxyphenyl)pyrrole-5-carboxylate
• Synonyms: ethyl 4-bromo-2-formyl-3-(4-methoxyphenyl)pyrrole-5-carboxylate
• CAS NO: 1587692-61-2
• Molecular Weight: 352.184
• Mol File: 1587692-61-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 4-bromo-2-formyl-3-(4-methoxyphenyl)pyrrole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-bromo-2-formyl-3-(4-methoxyphenyl)pyrrole-5-carboxylate(1587692-61-2)
• EPA Substance Registry System: ethyl 4-bromo-2-formyl-3-(4-methoxyphenyl)pyrrole-5-carboxylate(1587692-61-2)

Safety Data

• Hazardous Substances Data: 1587692-61-2(Hazardous Substances Data)

Upstream product

• 433267-55-1 4-bromo-1H-pyrrole-2-carboxylic acid ethyl ester 
• 1036356-17-8 ethyl 2-formyl-3-(4-methoxyphenyl)pyrrole-5-carboxylate 
• 1587692-53-2 4-bromo-5-formyl-1H-pyrrole-2-carboxylic acid ethyl ester 

Downstream Products

• 1587692-64-5 ethyl 2-formyl-3-(4-methoxyphenyl)-4-(4-methylphenyl)pyrrole-5-carboxylate 
• 1036355-83-5 3,4-bis-(4-methoxyphenyl)pyrrole-2,5-dicarboxylic acid monoethyl ester 
• 2234-38-0 3,4-bis(4-methoxyphenyl)-1H-pyrrole-2,5-dicarboxylic acid 
• 1036356-25-8 ethyl 5-formyl-3,4-bis(4-methoxyphenyl)pyrrole-2-carboxylate 

Relevant articles and documents

Formyl group activation of a bromopyrrole ester in Suzuki cross-coupling reactions: Application to a formal synthesis of Polycitone A and B and Polycitrin A

A new pyrrole building block is described, which allows for the regiospecific synthesis of 2,3,5-trisubstituted pyrroles and 2,3,4,5-tetrasubstituted pyrroles. Optimization studies are presented for the preparation of the pyrrole building block along with the evaluation of various cross-coupling conditions and cross-coupling agents. A short, formal synthesis of the natural products Polycitone A, Polycitone B, and Polycitrin A from the pyrrole building block is also described.