158792-27-9 Usage
Uses
Used in Pharmaceutical Industry:
Geninthiocin is used as a thiopeptide antibiotic tipA gene activator for its potent activation of the tipA gene, which is a bacterial transcription regulator involved in multidrug resistance. This property makes geninthiocin a valuable compound in the development of new antibiotics and treatments for drug-resistant bacterial infections.
Used in Oncology Research:
Geninthiocin is used as a research tool for studying the role of the tipA gene in multidrug resistance and its potential applications in oncology. Its close relationship to siomycin, an inhibitor of the oncogenic transcription factor FoxM1, suggests that geninthiocin may also have potential applications in cancer research and treatment.
Used in Antibacterial Applications:
Geninthiocin is used as an antibiotic for its activity against a variety of Gram-positive bacteria, the Gram-negative bacterium C. violaceum, and the fungus M. hiemalis. Its 10-fold selectivity for bacteria over mammalian cell lines makes it a promising candidate for the development of new antibiotics with reduced side effects on human cells.
Check Digit Verification of cas no
The CAS Registry Mumber 158792-27-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,8,7,9 and 2 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 158792-27:
(8*1)+(7*5)+(6*8)+(5*7)+(4*9)+(3*2)+(2*2)+(1*7)=179
179 % 10 = 9
So 158792-27-9 is a valid CAS Registry Number.
InChI:InChI=1/C50H49N15O15S/c1-12-27-48-61-30(16-79-48)41(72)54-21(5)39(70)65-35(50(10,11)77)45(76)57-23(7)47-64-33(25(9)80-47)44(75)55-20(4)38(69)56-22(6)46-60-29(15-78-46)34-26(49-62-31(17-81-49)42(73)63-32(24(8)66)43(74)59-27)13-14-28(58-34)40(71)53-19(3)37(68)52-18(2)36(51)67/h12-17,24,32,35,66,77H,2-7H2,1,8-11H3,(H2,51,67)(H,52,68)(H,53,71)(H,54,72)(H,55,75)(H,56,69)(H,57,76)(H,59,74)(H,63,73)(H,65,70)/b27-12+
