15885-62-8

Basic information

• Product Name: N'-Cycloheptylideneisonicotinic hydrazide
• Synonyms: N'-Cycloheptylideneisonicotinic hydrazide
• CAS NO: 15885-62-8
• Molecular Formula: C13H17 N3 O
• Molecular Weight: 231.2936
• Mol File: 15885-62-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.17g/cm³
• CAS DataBase Reference: N'-Cycloheptylideneisonicotinic hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-Cycloheptylideneisonicotinic hydrazide(15885-62-8)
• EPA Substance Registry System: N'-Cycloheptylideneisonicotinic hydrazide(15885-62-8)

Safety Data

• Hazardous Substances Data: 15885-62-8(Hazardous Substances Data)

Upstream product

• 1570-45-2 isonicotinic acid ethylester 
• 55-22-1 pyridine-4-carboxylic acid 
• 54-85-3 isoniazid 
• 502-42-1 cycloheptanone 

Relevant articles and documents

Synthesis, antimycobacterial, antiviral, antimicrobial activities, and QSAR studies of isonicotinic acid-1-(substituted phenyl)-ethylidene/cycloheptylidene hydrazides

A series of isonicotinic acid-1-(substituted phenyl)-ethylidene/ cycloheptylidene hydrazide derivatives (1-12) was tested for their, in vitro antimycobacterial activity against Mycobacterium tuberculosis, and compound 2 was found to be more active than isoniazid. The antiviral screening results indicated that none of the tested compounds was active against a broad variety of DNA and RNA viruses at subtoxic concentrations, except compounds 8 and 10 that proved to be active against DNA viruses at concentrations close to their cytostatic potential. The synthesized compounds were also screened for their antimicrobial potential against S. aureus, B. subtilis, E. coli, C. albicans and A. niger, and the results indicated that compounds having Br, OCH3 and Cl groups were highly active. The multi-target QSAR models indicated the importance of lipophilic (log P) and topological parameters (3vv) in describing the antimicrobial activity.