15886-23-4

Basic information

• Product Name: N-(prop-2-en-1-yl)-2-(pyridin-4-ylcarbonyl)hydrazinecarbothioamide
• Synonyms: 4-pyridinecarboxylic acid, 2-[(2-propen-1-ylamino)thioxomethyl]hydrazide; N1-allyl-2-(4-pyridylcarbonyl)hydrazine-1-carbothioamide; N-Allyl-2-isonicotinoylhydrazinecarbothioamide
• CAS NO: 15886-23-4
• Molecular Formula: C₁₀H₁₂N₄OS
• Molecular Weight: 236.2935
• Mol File: 15886-23-4.mol
• Article Data: 8

Chemical Properties

• Density: 1.242g/cm³
• Refractive Index: 1.611
• CAS DataBase Reference: N-(prop-2-en-1-yl)-2-(pyridin-4-ylcarbonyl)hydrazinecarbothioamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(prop-2-en-1-yl)-2-(pyridin-4-ylcarbonyl)hydrazinecarbothioamide(15886-23-4)
• EPA Substance Registry System: N-(prop-2-en-1-yl)-2-(pyridin-4-ylcarbonyl)hydrazinecarbothioamide(15886-23-4)

Safety Data

• Hazardous Substances Data: 15886-23-4(Hazardous Substances Data)

Upstream product

• 54-85-3 isoniazid 
• 57-06-7 N-allyl isothiocyanate 

Downstream Products

• 578760-61-9 C₂₁H₂₃N₅OS 
• 90842-92-5 4-(prop-2-en-1-yl)-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol 
• 90842-92-5 4-allyl-5-pyridin-4-yl-2,4-dihydro-3H-1,2,4-triazole-3-thione 

Relevant articles and documents

Isonicotinoylhydrazothiazoles and isonicotinoyl-N4-substituted thiosemicarbazides: Synthesis, characterization, and anti-mycobacterial activity

Differently substituted isonicotinoylhydrazothiazoles and isonicotinoyl-N4-substituted thiosemicaibazides have been prepared and characterized by means of elemental analysis, 1H-NMR, 13C-NMR, and Mass spectrometry. All the

A first-in-class anticancer dual HDAC2/FAK inhibitors bearing hydroxamates/benzamides capped by pyridinyl-1,2,4-triazoles

Novel 5-pyridinyl-1,2,4-triazoles were designed as dual inhibitors of histone deacetylase 2 (HDAC2) and focal adhesion kinase (FAK). Compounds 5d, 6a, 7c, and 11c were determined as potential inhibitors of both HDAC2 (IC50 = 0.09–1.40 μM) and F

Narrow SAR in odorant sensing Orco receptor agonists

The systematic exploration of a series of triazole-based agonists of the cation channel insect odorant receptor is reported. The structure-activity relationships of independent sections of the molecules are examined. Very small changes to the compound structure were found to exert a large impact on compound activity. Optimal substitutions were combined using a 'mix-and-match' strategy to produce best-in-class compounds that are capable of potently agonizing odorant receptor activity and may form the basis for the identification of a new mode of insect behavior modification.