158861-67-7

Basic information

• Product Name: Pralmorelin
• Synonyms: (2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-naphthalen-2-yl-propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]-N-[(2R)-2-aminopropanoyl]hexanamide;D-Ala-bata-(2-naphthyl)-D-Ala-Trp-D-Phe-Lys amide;D-Alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide;GHCA;D-ALANYL-3-(2-NAPHTHALENYL)-D-ALANYL-L-ALANYL-L-TRYPTOPHYL-D-PHENYLALANYL-L-LYSINAMIDE ACETATE ADDUCT;GHRP-2 (FREE PEPTIDE);D-Ala-D-β-Nal-Ala-Trp-D-Phe-Lys-NH2;4-dichloro-1
• CAS NO: 158861-67-7
• Molecular Formula: C42H50N8O5
• Molecular Weight: 746.91
• Product Categories: Peptide;Peptides
• Mol File: 158861-67-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 1186.79 °C at 760 mmHg
• Flash Point: 671.546 °C
• Appearance: /
• Density: 1.27 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.638
• Storage Temp.: −20°C
• Solubility: DMSO (Slightly, Sonicated), Water (Slightly)
• PKA: 13.40±0.46(Predicted)
• CAS DataBase Reference: Pralmorelin(CAS DataBase Reference)
• NIST Chemistry Reference: Pralmorelin(158861-67-7)
• EPA Substance Registry System: Pralmorelin(158861-67-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 158861-67-7(Hazardous Substances Data)

Usage

Uses

Growth hormone releasing factor. Pralmorelin is a growth hormone secretagogue that acts on the pituitary gland and the hypothalamus to stimulate and amplify pulsatile growth hormone release.

Biochem/physiol Actions

Pralmorelin, also known as Growth hormone-releasing peptide 2 or GHRP-2, is an orally-active, synthetic peptide analogue of met-enkephalin that acts as a ghrelin/growth hormone secretagogue receptor (GHSR) agonist to selectively stimulate the ghrelin receptor and cause growth hormone release. Pralmorelin (GHRP-2) has been used clinically for the assessment of growth hormone deficiency (GHD), It has also been shown to have anti-inflammatory activity.

InChI:InChI=1/C45H55N9O6/c1-27(47)41(56)52-38(24-30-19-20-31-14-6-7-15-32(31)22-30)43(58)50-28(2)42(57)53-39(25-33-26-49-35-17-9-8-16-34(33)35)45(60)54-37(23-29-12-4-3-5-13-29)44(59)51-36(40(48)55)18-10-11-21-46/h3-9,12-17,19-20,22,26-28,36-39,49H,10-11,18,21,23-25,46-47H2,1-2H3,(H2,48,55)(H,50,58)(H,51,59)(H,52,56)(H,53,57)(H,54,60)/t27-,28+,36+,37-,38-,39+/m1/s1